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Thomas E Lane Selected Research

Proteins (Proteins, Gene)

11/2020Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system.
1/2019Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis.
6/2014Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis.
9/2011Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity.
9/2006Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate.

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Thomas E Lane Research Topics

Disease

47Infections
01/2022 - 01/2002
32Demyelinating Diseases (Demyelinating Disease)
11/2020 - 04/2002
18Virus Diseases (Viral Diseases)
07/2019 - 04/2003
13Neuroinflammatory Diseases
01/2020 - 02/2006
12Inflammation (Inflammations)
01/2022 - 04/2003
12Multiple Sclerosis
01/2019 - 04/2004
5Coronavirus Infections
01/2022 - 08/2003
5Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2020 - 02/2004
5Persistent Infection
07/2019 - 01/2006
4Central Nervous System Infections (Central Nervous System Infection)
01/2022 - 06/2008
3Chronic Disease (Chronic Diseases)
01/2019 - 01/2006
3Encephalomyelitis (Myeloencephalitis)
08/2014 - 11/2009
3Central Nervous System Diseases (CNS Diseases)
01/2014 - 02/2002
3Acute Disease
01/2013 - 01/2006
3Herpetic Keratitis
03/2006 - 09/2003
2Malaria
01/2020 - 01/2013
2Paralysis (Palsy)
01/2019 - 06/2004
2Encephalitis (Encephalitis, Rasmussen)
12/2008 - 03/2008
2Hepatitis
12/2008 - 07/2007
2Autoimmune Diseases (Autoimmune Disease)
06/2008 - 04/2008
2Liver Diseases (Liver Disease)
03/2008 - 07/2007
1COVID-19
01/2022
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019
1Neoplasms (Cancer)
10/2018
1Lung Neoplasms (Lung Cancer)
10/2018
1Disease Progression
01/2016
1Infarction (Infarctions)
10/2015
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2015
1Spinal Cord Injuries (Spinal Cord Injury)
09/2013
1Alzheimer Disease (Alzheimer's Disease)
09/2013
1Nervous System Diseases (Neurological Disorders)
09/2013
1Crush Injuries
06/2012
1Cysts
01/2012
1Necrosis
09/2011

Drug/Important Bio-Agent (IBA)

23ChemokinesIBA
01/2022 - 01/2002
15LigandsIBA
01/2013 - 04/2003
14CytokinesIBA
01/2022 - 03/2006
10CXC ChemokinesIBA
06/2010 - 01/2004
7CC ChemokinesIBA
06/2006 - 04/2003
6Chemokine ReceptorsIBA
01/2022 - 01/2003
5Antiviral Agents (Antivirals)IBA
01/2022 - 09/2003
5Proteins (Proteins, Gene)FDA Link
11/2020 - 09/2006
5AntigensIBA
07/2019 - 01/2004
5Chemotactic FactorsIBA
01/2013 - 04/2002
4RNA (Ribonucleic Acid)IBA
01/2022 - 01/2010
3Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2022 - 11/2004
3NK Cell Lectin-Like Receptor Subfamily KIBA
10/2014 - 03/2008
3Viral AntigensIBA
01/2010 - 09/2003
3CXCR3 ReceptorsIBA
09/2009 - 03/2006
3Chemokine CXCL10IBA
08/2008 - 09/2003
3CCR5 Receptors (CCR5 Receptor)IBA
03/2006 - 08/2003
2Eukaryotic Initiation Factor-2 (EIF 2)IBA
01/2022 - 11/2021
2K-18 conjugate (K18)IBA
01/2022 - 11/2021
2Chemokine CXCL9IBA
01/2022 - 11/2021
2Messenger RNA (mRNA)IBA
11/2020 - 02/2004
2Apolipoproteins E (ApoE)IBA
11/2020 - 10/2015
2Transcription Factors (Transcription Factor)IBA
07/2019 - 10/2018
2Chemokine CXCL1IBA
01/2018 - 02/2016
2Fingolimod Hydrochloride (FTY720)FDA Link
10/2015 - 08/2014
2Interleukin-6 (Interleukin 6)IBA
09/2014 - 01/2004
2Pharmaceutical PreparationsIBA
08/2014 - 07/2010
2LipopolysaccharidesIBA
11/2012 - 06/2011
2Chemokine CCL5IBA
07/2010 - 05/2005
2CuprizoneIBA
07/2010 - 03/2010
2Interferon-gamma (Interferon, gamma)IBA
03/2008 - 01/2006
2CCR2 ReceptorsIBA
06/2006 - 11/2004
1ApolipoproteinsIBA
11/2020
1OsteopontinIBA
11/2020
1Macrophage Colony-Stimulating FactorIBA
11/2020
1PLX5622IBA
11/2020
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2020
1Interleukin-2 (IL2)IBA
07/2019
1AutoantigensIBA
07/2019
1TamoxifenFDA LinkGeneric
01/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1SOXB1 Transcription FactorsIBA
10/2018
1Polystyrenes (Polystyrene)IBA
01/2018
1Capsules (Microcapsules)IBA
01/2018
1Carcinoembryonic AntigenIBA
11/2017
1Cell Adhesion MoleculesIBA
11/2017
1MicroRNAs (MicroRNA)IBA
01/2017
1Glial Fibrillary Acidic ProteinIBA
02/2016
1Tetracycline (Achromycin)FDA LinkGeneric
02/2016
1CholesterolIBA
10/2015
1Sphingosine-1-Phosphate ReceptorsIBA
10/2015
1Green Fluorescent ProteinsIBA
06/2014
1Interleukin-27 (Interleukin 27)IBA
01/2013
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
03/2012
1MetalsIBA
03/2012
1ChitinasesIBA
01/2012
1plerixaforFDA Link
12/2011
1Fas-Associated Death Domain Protein (Fas-Associating Protein with Death Domain)IBA
09/2011
1Death Domain ReceptorsIBA
09/2011
1CaspasesIBA
09/2011
1Glycogen Synthase (Synthase I)IBA
06/2011

Therapy/Procedure

11Transplantation
01/2020 - 06/2004
5Therapeutics
01/2019 - 07/2010
2Cell Transplantation
01/2019 - 01/2016
2Laminectomy
06/2012 - 11/2010
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2022